Rap2 and TNIK control Plexin-dependent tiled synaptic innervation in C. elegans
During development, neurons form synapses with their fate-determined targets.While we begin to elucidate the mechanisms by which extracellular ligand-receptor interactions enhance synapse specificity by inhibiting synaptogenesis, our knowledge about their intracellular mechanisms remains limited.Here we show that Rap2 GTPase (rap-2) and its effecto